Matthew B. Gretzer, MD, FACS

Professor, Urology
Director, Genitourinary Reconstructive Surgery
Academic Professional Bio: 

Matthew Gretzer, MD, is a clinical professor and the director of genitourinary reconstructive surgery at the University of Arizona Department of Urology, College of Medicine - Tucson. Dr. Gretzer specializes in the management of urethral stricture disease and is one of only a few Arizona urologists that routinely performs a high volume of complex urethral reconstruction (urethroplasty) cases. In addition, he has advanced urologic training in all aspects of genitourinary reconstruction and prosthetics and performs numerous penile implant and artificial urinary sphincter cases, both initial and revisional as referred from other urologists. The highly complex nature of these procedures improves the quality of life for these patients following cancer therapy and traumatic injury. 

Since joining the University of Arizona Division of Urology faculty in 2005, Dr. Gretzer has established the Department of Urology as a center of excellence in genitourinary reconstruction. When he arrived, there were no other urethral reconstruction specialists in Arizona. He has since worked hard to develop a wide referral network that spans all of Arizona as well as all of its neighboring states. As this program has matured in Arizona, patients are now routinely referred to the University of Arizona in Tucson for this unique management of their treatment instead of being referred out of state.

"I treat everyone as I would want to be treated and strive to maintain accessibility, communication, and above" - Matthew Gretzer, MD, FACS.

Research Interests: 

New therapy for male incontinence
Urethral stricture management outcomes
Genitourinary trauma management
Voiding fluid dynamics

  1. MD: University of Texas Health Science Center - San Antonio, 1998
Honors and Awards:
  • Arizona Representative to the Western Section American Urological Association
  • President of the Arizona Urological Society
  • Johns Hopkins Hospital, General Surgery, 1999
  • Johns Hopkins Hospital/School of Medicine, General Surgery Resident, 2000
  • Johns Hopkins Hospital/School of Medicine, James Buchanan Brady Urological Institute, Urology, 2004
  • Johns Hopkins Hospital, James Buchanan Brady Urological Institute, Advanced Urological Training, 2004-2005
Board Certifications:
  • American Board of Urology, Diplomate
  • Fellow American College of Surgeons



Pollock, G. R., A. Bergersen, F. M. Chaus, and M. Gretzer, "Pelvic Hematoma Following UroLift procedure for BPH.", Urology, vol. 133, pp. e3-e4, 2019 Nov.
Nash, S., S. Aboseif, P. Gilling, M. Gretzer, H. Samowitz, M. Rose, J. Slutsky, S. Siegel, and L. Mai Tu, "Four-year follow-up on 68 patients with a new post-operatively adjustable long-term implant for post-prostatectomy stress incontinence: ProACT™.", Neurourol Urodyn, vol. 38, issue 1, pp. 248-253, 2019 01.
Pollock, G. R., and M. Gretzer, "Pelvic Hematoma following UroLift procedure for BPH: Letter in response to reader comments.", Urology, 2019 Dec 19.


DeLay, K. J., N. M. Haney, J. Chiang, C. Stewart, F. A. Yafi, K. Angermeier, H. Wood, T. Boone, A. G. Kavanagh, M. Gretzer, et al., "Comparison of Adjuvant Radiation Therapy Before or After Artificial Urinary Sphincter Placement: A Multi-Institutional, Retrospective Analysis.", Urology, vol. 113, pp. 160-165, 2018 03.
Nash, S., S. Aboseif, P. Gilling, M. Gretzer, H. Samowitz, M. Rose, J. Slutsky, S. Siegel, and L. Mai Tu, "Treatment with an adjustable long-term implant for post-prostatectomy stress incontinence: The ProACT™ pivotal trial.", Neurourol Urodyn, vol. 37, issue 8, pp. 2854-2859, 2018 11. PMID: 30178536


Dyer, A., P. M. Sadow, E. Bracamonte, and M. Gretzer, "Immunoglobulin G4-related Retroperitoneal Fibrosis of the Pelvis.", Rev Urol, vol. 16, issue 2, pp. 92-4, 2014. PMCID: PMC4080856 


Nguyen, M. M., F. R. Ahmann, R. B. Nagle, C-H. Hsu, J. A. Tangrea, H. L. Parnes, M. H. Sokoloff, M. B. Gretzer, and H-H. Sherry Chow, "Randomized, double-blind, placebo-controlled trial of polyphenon E in prostate cancer patients before prostatectomy: evaluation of potential chemopreventive activities.", Cancer Prev Res (Phila), vol. 5, issue 2, pp. 290-8, 2012 Feb. PMCID: PMC3273617  PMID: 22044694


Sroka, I. C., T. A. Anderson, K. M. McDaniel, R. B. Nagle, M. B. Gretzer, and A. E. Cress, "The laminin binding integrin alpha6beta1 in prostate cancer perineural invasion.", J Cell Physiol, vol. 224, issue 2, pp. 283-8, 2010 Aug. PMCID: PMC4816210  PMID: 20432448


Malik, G., E. Rojahn, M. D. Ward, M. B. Gretzer, A. W. Partin, J. O Semmes, and R. W. Veltri, "SELDI protein profiling of dunning R-3327 derived cell lines: identification of molecular markers of prostate cancer progression.", Prostate, vol. 67, issue 14, pp. 1565-75, 2007 Oct 01. PMID: 17705230


Gretzer, M. B., and A. W. Partin, "Advances in prostate cancer treatment: highlights from the 2nd international prostate cancer congress, st. Thomas, u.s. Virgin islands, july 17-20, 2002.", Rev Urol, vol. 5, issue 2, pp. 111-7, 2003 Spring. PMCID: PMC1473003